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This book seeks to narrow two gaps: first, between the widespread use of case studies and their frequently ‘loose’ methodological moorings; and second, between the scholarly community advancing methodological frontiers in case study research and the users of case studies in development policy and practice. It draws on the contributors’ collective experience at this nexus, but the underlying issues are more broadly relevant to case study researchers and practitioners in all fields. How does one prepare a rigorous case study? When can causal inferences reasonably be drawn from a single case? When and how can policy-makers reasonably presume that a demonstrably successful intervention in one context might generate similarly impressive outcomes elsewhere, or if massively ‘scaled up’? No matter their different starting points – disciplinary base, epistemological orientation, sectoral specialization, or practical concerns – readers will find issues of significance for their own field, and others across the social sciences. This title is also available Open Access.